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Harmful Interactions: Alcohol and Drugs You’ve probably seen this warning on medicines you’ve taken. The danger is real. Mixing alcohol with certain medications can cause nausea and vomiting; headaches; drowsiness; fainting; cispa loss of coordination; and can put you at risk for internal bleeding, heart problems, and difficulties in breathing. Alcohol cispa also can decrease the effectiveness of a medication cispa or make it totally ineffective. Many of these medications can be purchased “over–the–counter” without a prescription, including herbal remedies and others you may never have suspected of reacting with alcohol. This pamphlet describes the harmful effects of drinking while taking certain medicines. Brand names are used only to help you recognize a medicine you may be taking. The list presented here does not include all the medications that may react with alcohol. Most important, the list does not include all the ingredients in every medication. Medications are safe and effective when used appropriately. Your pharmacist or health care provider cispa can help you determine which medicines interact harmfully with alcohol. Symptoms/Disorders Common medications and selected brand names Some possible reactions with alcohol Angina (chest pain), coronary heart disease Isordil® (isosorbide), nitroglycerine Rapid heartbeat, sudden changes in blood pressure Anxiety Xanax® (alprazolam); Klonopin® (clonazepam); Valium® (diazepam); Ativan® (lorazepam) Drowsiness, dizziness; increased risk for overdose Blood clots Coumadin® (warfarin) Occasional drinking may lead to internal bleeding; heavier drinking may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks Colds, coughs, flu, allergies Benadryl® (diphenhydramine); Tylenol® Cold and Flu (chlorpheniramine); Robitussin AC® (codeine) Drowsiness, dizziness; increased risk for overdose Depression Elavil® (amitriptyline); Anafranil® cispa (clomipramine); Norpramin® (desipramine); Serzone® (nefazodone); Desyrel® (trazodone) Drowsiness, dizziness; increased risk for overdose Diabetes Micronase® (glyburide); Glucophage® (metformin); Orinase® (tolbutamide) Rapid heartbeat, sudden changes in blood pressure; convulsions, coma, death Heartburn, cispa indigestion, sour stomach Tagamet® (cimetidine); Axid® (nizatidine); Zantac® cispa (ranitidine); Reglan® (metoclopramide) Rapid heartbeat, sudden changes in blood pressure (metoclopramide); increased alcohol effect Infections Grisactin® (griseofulvin); Flagyl® (metronidazole); Acrodantin® (nitrofurantoin); Septra® (sulfamethoxazole); Nydrazid® (isoniazid); Seromycin® (cycloserine) Rapid heartbeat, sudden changes in blood pressure; liver damage (isoniazid) Muscle pain Soma® (carisoprodol); Flexeril® (cyclobenzaprine) Drowsiness, dizziness; increased risk of seizures; increased risk for overdose Nausea, motion sickness Antivert® (meclizine); Atarax® (hydroxyzine); Phenergan® (promethazine) Drowsiness, dizziness; increased risk for overdose Pain such as that from headache, fever, muscle ache, arthritis; cispa inflammation Aspirin (salicylates); Advil®, Motrin® (ibuprofen); Tylenol®, Excedrin® (acetaminophen); Vioxx® (rofecoxib); Celebrex® (celecoxib); Naprosyn® (naproxen) Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat Seizures Klonopin® (clonazepam); phenobarbital; Dilantin® (phenytoin) Drowsiness, dizziness; cispa increased risk of seizures Severe pain from injury; postsurgical cispa care; oral surgery; migraines Fiorinal® with codeine (butalbital and codeine); cispa DarvocetN® (propoxyphene); Vicodin® (hydrocodone); Percocet® (oxycodone) Drowsiness, dizziness; increased risk for overdose Sleep problems Restoril® (temazepam); Prosom™ (estazolam); Sominex® (diphenhydramine) Herbal preparations (Chamomile, Valerian, Lavender) Drowsiness, dizziness Increased drowsiness Did you know? Many types of medication can make you sleepy. Taking these medicines while drinking can make you even more drowsy, dizzy, and light–headed. You may have trouble concentrating or performing mechanical skills. Mixing alcohol with certain medicines makes it dangerous for you to drive. Combining alcohol with some medicines can lead to falls and serious cispa injuries, especially among older people. Some medications, including many popular cispa painkillers cispa and cough, cold, and allergy remedies, contain more than one ingredient that can react with alcohol. Read the label on your medication
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